OBSTRUCTIVE SLEEP APNEA RISK AND LONGITUDINAL TRAJECTORY OF FUNCTIONAL HEARING LOSS OVER EIGHT YEARS OF FOLLOW-UP

Abstract Hearing loss prevention is important for physical, cognitive and psychosocial health among older adults. Obstructive sleep apnea (OSA) might cause functional hearing loss through ischemic damages to the cochlea or central auditory processing, but there is a lack of longitudinal evidence. The National Health and Aging Trends Study (NHATS) is a longitudinal panel survey of Medicare beneficiaries aged 65+ years. STOP-Bang is a validated screening tool for OSA risk and a subsample of NHATS round 3 participants responded to a modified version (age>50, male, high blood pressure, body mass index >35 kg/m2, snore loudly, observed apnea, tiredness; range 0-7, elevated risk if ≥3). Functional hearing loss at follow-up (rounds 3-11) was defined as self-reported deafness, hearing aid use, or inability to hear well enough to use the telephone or have conversations in a room with the television or radio on. We used generalized estimating equations logistic regression with inverse probability attrition weighting, adjusting for demographics and comorbidities. Among 1,433 participants, elevated OSA (58%) was associated with higher odds of hearing loss at baseline (odds ratio:1.50, 95% confidence interval[CI]:1.08, 2.10). Both OSA groups had significant annual increases in odds of functional hearing loss (Low:1.07, 95% CI:1.01, 1.13; Elevated:1.12, 95% CI:1.07, 1.18) during the first 4 years. Afterwards, the low OSA risk group continued to have significant increase in odds of functional hearing loss but not the elevated OSA risk group. OSA might be a novel risk factor for hearing loss. Screening and treating OSA might be important for hearing loss prevention.

and Diane Lim 3 , 1. University of Nevada,Las Vegas,Las Vegas,Nevada,United States,2. University of Southern California,Los Angeles,California,United States,3. Miami VA Healthcare System,Miami,Florida,United States Emerging evidence suggests that night shift workers are at higher risk of severe cognitive impairment, mainly because of the repeated disruption of the sleep-wake schedule and the resulting poor sleep (e.g., less deep sleep or shorter sleep time).However, questions remain about how daytime and nighttime sleep characteristics correlate with cognitive performance in shift workers.The purpose of this study is to examine the association of objective sleep quality, measured on workdays and days off, with cognitive performance, determined by the psychomotor vigilance task (PVT), in shift workers compared to day workers.We included eight night shift and ten day shift workers from an ongoing pilot study in this analysis.Participants undergo multiple home sleep studies with electroencephalograms on their workdays or days off.Sleep quality measures include total sleep time (TST), percentage of deep sleep stage in TST, and wake time after sleep onset (WASO).Night shift workers showed longer TST and shorter WASO during their nighttime sleep on days off compared to day shift workers.In night shift workers, longer deep sleep on days off was significantly correlated with faster mean reaction time to a visual stimulus (better cognitive performance) on the PVT (r = -.944,p = .016),after controlling for age.However, longer deep sleep during their daytime sleep was associated with slower reaction time (r = .756,p = .049).Further studies are necessary to elucidate differential impacts of daytime and nighttime sleep on the risk of future cognitive impairment in night shift workers.

OBSTRUCTIVE SLEEP APNEA RISK AND LONGITUDINAL TRAJECTORY OF FUNCTIONAL HEARING LOSS OVER EIGHT YEARS OF FOLLOW-UP
Kening Jiang 1 , Adam Spira 1 , Nicholas Reed 1 , Frank Lin 2 , and Jennifer Deal 3 , 1. Johns Hopkins Bloomberg School of  Public Health, Baltimore, Maryland, United States, 2. Johns  Hopkins, Baltimore, Maryland, United States, 3. Johns  Hopkins University, Baltimore, Maryland, United States  Hearing loss prevention is important for physical, cognitive and psychosocial health among older adults.Obstructive sleep apnea (OSA) might cause functional hearing loss through ischemic damages to the cochlea or central auditory processing, but there is a lack of longitudinal evidence.The National Health and Aging Trends Study (NHATS) is a longitudinal panel survey of Medicare beneficiaries aged 65+ years.STOP-Bang is a validated screening tool for OSA risk and a subsample of NHATS round 3 participants responded to a modified version (age>50, male, high blood pressure, body mass index >35 kg/m2, snore loudly, observed apnea, tiredness; range 0-7, elevated risk if ≥3).Functional hearing loss at follow-up (rounds 3-11) was defined as selfreported deafness, hearing aid use, or inability to hear well enough to use the telephone or have conversations in a room with the television or radio on.We used generalized estimating equations logistic regression with inverse probability attrition weighting, adjusting for demographics and comorbidities.Among 1,433 participants, elevated OSA (58%) was associated with higher odds of hearing loss at baseline (odds ratio:1.50,95% confidence interval[CI]:1.08,2.10).Both OSA groups had significant annual increases in odds of functional hearing loss (Low:1.07,95% CI:1.01, 1.13; Elevated:1.12, 95% CI:1.07, 1.18) during the first 4 years.Afterwards, the low OSA risk group continued to have significant increase in odds of functional hearing loss but not the elevated OSA risk group.OSA might be a novel risk factor for hearing loss.Screening and treating OSA might be important for hearing loss prevention.Such studies can open a window to better understanding of the aging process.We aim to explore the link between sleep quality and gait among community-dwelling midlife adults.We recruited 103 midlife adults (age 59.3±7).Gait was evaluated with the cognitive Dual-Task (DT) paradigm.Gait speed and variability were assessed with the APDM mobility lab.Sleep quality was evaluated objectively using one-week actigraphy and subjectively using the Pittsburg Sleep Quality Index (PSQI).We found that age was significantly associated with earlier bedtime (p=0.007),lower sleep efficiency (p=0.01) and increased wake after sleep onset (p=0.01).Sex differences were found for objective and subjective sleep duration (actigraphy and PSQI, p=0.002 and p< 0.001, respectively), with women sleeping significantly more than men.No sex differences were found for sleep efficiency.A significant main effect was found for actigraphy-based sleep duration (short/ intermediate/long) on gait speed, such that gait speed was slower in long compared to short and intermediate sleepers under DT only (p=0.018).To conclude, a negative association between sleep quality and gait speed under DT was found, showing adverse health outcomes for long versus short and intermediate sleepers in midlife.

THE M. POWELL LAWTON AWARD LECTURE AND PRESENTATION Chair: Tiffany Washington
The M. Powell Lawton Award Lecture will feature an address by the 2022 recipient Jon Pynoos, PhD, FGSA, FAGHE, of the University of Southern California.This session will also include the presentation of the 2023 M. Powell Lawton Award to recipient.The M. Powell Lawton Award is presented annually to an individual who has made outstanding contributions from applied research that has benefited older people and their care.Aging in place remains a high priority of older adults.However, the home environments in which they reside often have hazards and lack supportive features, putting them at risk of falls and making it difficult to carry out daily activities.People who need home modifications the most (i.e., vulnerable populations) are the least likely to have them.In response to the needs of the growing population of older adults, there has been notable progress in the field.Now, with an increasing recognition of the impact of housing on health, there are new opportunities to move the field forward.Highlighting Powell Lawton's contributions as a foundation, this lecture will: 1) review major developments in research, service delivery, policy, and consumer education, and 2) discuss recommendations for action that practitioners, researchers, policymakers, and advocates could undertake to realize Lawton's vision of home environments that support aging for all.

MEANINGFUL MODERATORS AND PATHWAYS
Abstract citation ID: igad104.1622

DETERMINANTS OF INFORMAL CARE TRAJECTORIES IN ENGLAND
Giorgio Di Gessa 1 , and Christian Deindl 2 , 1. University College London, London, England, United Kingdom, 2. TU Dortmund University, Dortmund, Nordrhein-Westfalen, Germany In the context of an ageing population, combined with long-standing challenges in the delivery of formal social care for older people, unpaid caregivers play a key role in promoting the quality of life of older people and their extended families and ensuring that needs for care and support are met.Although many studies have provided snapshots of informal care provision, few so far have examined longitudinal patterns of informal care provision among older people.This paper aims to describe caregiving trajectories in later life and to examine how socioeconomic, demographic, and health characteristics of older adults relate to these patterns (including needs and enabling factors).Using six waves of the English Longitudinal Study of Ageing, we conduct latent trajectory analysis to cluster people's diverse trajectories into a finite number of groups.The intensity of informal care provision is also considered when identifying longitudinal trajectories.Preliminary results show five distinct trajectories of informal care provision (including those who never provide informal care, those who provide sporadic informal care, those with increasing and decreasing commitment to care provision, and those who care throughout).Gender, age, health, income, living arrangements, and family compositions all relate to

WHAT CAN WE LEARN FROM THE LINK BETWEEN SLEEP AND GAIT ON THE AGING PROCESS?
Maayan Agmon 1 , Roy Tzemah-Shahar 2 , and Tamar Shochat 1 , 1. University of Haifa, Haifa, HaZafon, Israel, 2. University of Haifa, Ramat-Gan, HaZafon, Israel Falls are a major problem among older adults; and older adults with sleep complaints are at a four-fold risk of falls compared with those without sleep complaints.Recent studies demonstrate comorbidity between gait and sleep, which are two essential, modifiable, and age-sensitive functions.Yet, most studies were conducted on older adults, whereas studies on midlife adults are lacking.
The Lawton Award is generously funded by the Polisher Research Institute of Abramson Senior Care.